Prognostic factors for squamous cell cervical cancer
نویسنده
چکیده
3 Papers 4 Abbreviations 5 Introduction 6 Epidemiology 6 Incidence 7 Mortality 7 Etiology 7 Human papillomavirus 7 Cofactors 8 Smoking 8 Female sex steroid hormones 9 Other cofactors and riskfactors 9 Carcinogenesis 10 Biological markers 11 Tissue markers 11 Tissue markers in the present study 12 Other major tissue markers 15 Serum markers 15 DNA cytometry – S-phase fraction and ploidy 16 Histology 16 Histological type 16 Histological grade 16 Stage 16 Prevention 17 Primary prevention 17 Secondary prevention 18 Treatment 18 Prognosis 19 Clinical prognostic factors 19 Other prognostic factors 20 Aims of the Investigation 21 Materials and Methods 22 Patients 22 Flow cytometry 24 Ploidy 24 S-phase fraction 24 Hormone analyses 24 Tumor markers 25 Paraffin embedded tumor biopsy samples 25 Tissue microarray 25 Immunohistochemical analysis 25 Statistical analysis 27
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